초록접수 현황
| 17F-154 | 구연 발표 |
The Association between Morphological and Functional Characteristics of Bicuspid Aortic Valve and Bicuspid Aortopathy
Sung Jun Lee¹, Je Kyoun Shin¹, Hyun Keun Chee¹, Jun Suk Kim¹, Sung Min Ko²
¹Department of Thoracic and Cardiovascular Surgery, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea., ²Department of Radiology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea
Purpose : The aims of this study were to determine the association between morphological and functional characteristics of BAV and bicuspid aortopathy and to identify the determinants of aortic dilatation using CCT.
Methods : This study cohort included 282 subjects (206 men, age 52.3±14.5 years) who underwent both CCT and transthoracic echocardiography from 2008 to 2016. BAVs were classified as anterior-posterior (BAV-AP) or lateral (BAV-LA) orientation of the cusps and divided according to the presence (raphe+) or absence of a raphe (raphe–) based on CCT findings. The sinuses of Valsalva and proximal ascending aorta were measured by CCT.
Results : BAV-AP was present in 173 patients (61.3 %) and raphe+ in 168 (59.6 %). BAV morphotype and raphe+/- were not associate with aortic root and ascending aortic diameters. The aortic root diameter were significantly associated with AS severity ( p=0.021) and sex (p=0.006) and the ascending aorta diameter was associated with age (p<0.001). Patients with dilated aortic root (n=207) were older (p=0.019) and had a lower prevalence of male sex (p<0.028) and lower BSA(p<0.001). Patients with dilated ascending aorta (n=217) were older (p<0.001) and had lower prevalence of male sex (p<0.001), lower BSA (p<0.001), higher prevalence of hypertension (p=0.041), raphe+ (p=0.017), BAV-RL (p=0.039), moderate-to-severe AS (p<0.001) and none or mild aortic regurgitation (p<0.001). BSA was the sole independent determinant of aortic root diameter (p<0.001).
Conclusion : BAV morphotype and raphe+/- are not associated with aortic root and ascending aortic dilatation and not the determinants of aortic dilatation. Further studies are needed to investigate the discrepancy
Methods : This study cohort included 282 subjects (206 men, age 52.3±14.5 years) who underwent both CCT and transthoracic echocardiography from 2008 to 2016. BAVs were classified as anterior-posterior (BAV-AP) or lateral (BAV-LA) orientation of the cusps and divided according to the presence (raphe+) or absence of a raphe (raphe–) based on CCT findings. The sinuses of Valsalva and proximal ascending aorta were measured by CCT.
Results : BAV-AP was present in 173 patients (61.3 %) and raphe+ in 168 (59.6 %). BAV morphotype and raphe+/- were not associate with aortic root and ascending aortic diameters. The aortic root diameter were significantly associated with AS severity ( p=0.021) and sex (p=0.006) and the ascending aorta diameter was associated with age (p<0.001). Patients with dilated aortic root (n=207) were older (p=0.019) and had a lower prevalence of male sex (p<0.028) and lower BSA(p<0.001). Patients with dilated ascending aorta (n=217) were older (p<0.001) and had lower prevalence of male sex (p<0.001), lower BSA (p<0.001), higher prevalence of hypertension (p=0.041), raphe+ (p=0.017), BAV-RL (p=0.039), moderate-to-severe AS (p<0.001) and none or mild aortic regurgitation (p<0.001). BSA was the sole independent determinant of aortic root diameter (p<0.001).
Conclusion : BAV morphotype and raphe+/- are not associated with aortic root and ascending aortic dilatation and not the determinants of aortic dilatation. Further studies are needed to investigate the discrepancy
책임저자: Sung Min Ko
Department of Radiology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Republic of Korea
발표자: Sung Jun Lee, E-mail : 20150060@kuh.ac.kr