초록접수 현황
| 17F-259 | 구연 발표 |
Prevalence and Risk Factors of Reflux after Esophagectomy for Esophageal Cancer
Samina Park, Kwanyong Hyun, Hyun Joo Lee, In Kyu Park, Young Tae Kim, Chang Hyun Kang
Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea
Purpose : Reflux is a frequent symptom after esophagectomy. However, the intensity and presentation of reflux is quite diverse depending on the patients. Therefore, we assessed reflux symptoms using Reflux Symptom Index (RSI) questionnaire in patients who underwent esophageectomy for esophageal cancer.
Methods : From April, 2017 to July, 2017, we prospectively investigated patients who underwent esophagectomy for esophageal cancer at the out-patient clinic. The severity of reflux was evaluated with a self-administered nine-item outcomes instrument, grading 0 (none) to 5 (severe). A RSI score ≥ 13 was defined as a significant reflux.
Results : A total of 151 patients were included. The mean age was 64.1±8.8 years and the majority was male (n=136, 90.1%). The median time after esophagectomy was 22.6 months. A question regarding heart burn, chest pain, indigestion, or acid coming up was the most frequently being responded (n=104, 68.9%) (figure). 41 patients (27.2%) presented a significant reflux with the mean RSI score of 19.9±6.3. Administration of proton-pump inhibitor or prokinetics was not a predisposing factors for RSI score <13. Cervical anastomosis (OR=2.3, p-value=0.04) and follow up duration below 2 years (OR=3.5, p-value=0.002) were significant risk factors for RSI ≥ 13 in multi-variable analysis. Patients who underwent cervical anastomosis with follow up duration below 2 years had a higher risk (OR=6.7, p-value=0.005) compared to those underwent thoracic anastomosis with follow up duration over 2 years.
Conclusion : Reflux symptom was frequently reported after esophagectomy. We revealed that the location of anastomosis and short duration after esophagectomy were significant predisposing factors for a reflux after esophagectomy.
Methods : From April, 2017 to July, 2017, we prospectively investigated patients who underwent esophagectomy for esophageal cancer at the out-patient clinic. The severity of reflux was evaluated with a self-administered nine-item outcomes instrument, grading 0 (none) to 5 (severe). A RSI score ≥ 13 was defined as a significant reflux.
Results : A total of 151 patients were included. The mean age was 64.1±8.8 years and the majority was male (n=136, 90.1%). The median time after esophagectomy was 22.6 months. A question regarding heart burn, chest pain, indigestion, or acid coming up was the most frequently being responded (n=104, 68.9%) (figure). 41 patients (27.2%) presented a significant reflux with the mean RSI score of 19.9±6.3. Administration of proton-pump inhibitor or prokinetics was not a predisposing factors for RSI score <13. Cervical anastomosis (OR=2.3, p-value=0.04) and follow up duration below 2 years (OR=3.5, p-value=0.002) were significant risk factors for RSI ≥ 13 in multi-variable analysis. Patients who underwent cervical anastomosis with follow up duration below 2 years had a higher risk (OR=6.7, p-value=0.005) compared to those underwent thoracic anastomosis with follow up duration over 2 years.
Conclusion : Reflux symptom was frequently reported after esophagectomy. We revealed that the location of anastomosis and short duration after esophagectomy were significant predisposing factors for a reflux after esophagectomy.
책임저자: Chang Hyun Kang
Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea
발표자: Samina Park, E-mail : saminapark1203@gmail.com