Robotic Thymectomy in Thymic Epithelial Tumors: Propensity Score Matching Study of 112 Consecutive Cases
Samina Park, Kwanyong Hyun, Hyun Joo Lee, In Kyu Park, Young Tae Kim, Chang Hyun Kang
Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea
Purpose : Robotic thymectomy (RT) has emerged as an alternative to trans-sternal sternotomy (ST) for thymic epithelial tumors (TET). However, the evidence regarding oncological safety and outcomes of RT has been limited. We investigated oncological safety and outcomes of robotic total thymectomy for TET.
Methods : A total of 395 patients underwent total thymectomy for TET from March, 2000 to April, 2017. Among them, 112 patients underwent RT. Propensity score matching for potential confounders was performed between RT and ST, and 112 patients were included for each groups. We compared postoperative outcomes after RT compared to those of ST.
Results : In matched group, thymoma was the main histology in both groups (RT vs. ST; 80% vs 83%; p=0.618). Operative time (RT vs. ST; 173±97 minutes vs. 176±80 minutes; p=0.767) and postoperative complication rate (RT vs. ST; 8% vs. 13%; p=0.219) were similar between two groups. There was no postoperative mortality in both groups. The mean length of hospital stay was shorter in RT group (RT vs. ST; 4±5 days vs. 7±8 days; p=0.001). R0 resection was achieved in 100% in RT group and 97% in ST group. Combined resections was performed more frequently in ST group without statistical significance (RT vs. ST; 19 patients (17%) vs. 31 patients (28%); p=0.123). Five-year survival of each group was 100% in RT and 97.5% in ST, respectively (p=0.307).
Conclusion : We demonstrated comparable outcomes of robotic thymectomy in TET. RT could be applied to TET without jeopardizing oncological safety even in the cases of concomitant en-bloc resection of adjacent structures.
책임저자: Chang Hyun Kang
Department of Thoracic and Cardiovascular Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea
발표자: Samina Park, E-mail : saminapark1203@gmail.com