초록접수 현황

17F-268 구연 발표

Clinical Outcomes of Lung Transplantation: Experience at a Single Center
Se Hoon Choi, Yong Ho Jeong, Min Kyun Kang, Han Pil Lee, Byung Kwon Chong, Jin San Bok, Geun Dong Lee, Hyeong Ryul Kim, Yong-Hee Kim, Dong Kwan Kim, Seung-Il Park
Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, Ulsan University College of Medicine, Seoul, Republic of Korea

Purpose : Lung transplantation is a life-preserving treatment for patients with terminal lung diseases and is increasingly being performed in Korea. Aim of this study is to evaluate the outcomes of lung transplantation, and to compare the results according to preoperative condition.

Methods : All the patients who underwent lung transplantation till July 2017 were reviewed. Among 62 patients, 49 patients who received only lung transplantation were enrolled. We divided them in 2 groups according to the application of preoperative ECMO or ventilator.

Results : All 49 patients underwent bilateral sequential lung transplantation. A high percentage of patients received intensive care (32, 65.3%), including ventilator support (32,65.3%) and extracorporeal life support (25,51.0%) before transplantation. When we followed up for 2.2 years (3 days to 6.3 years), there were 12 mortalities including 5 cases before 30 postoperative days. One-, 3-, 5-year survival rates of all patients were 76.1%, 72.1%, and 68.0%, respectively. In preoperative ECMO/Ventilator group, postoperative ICU stay was longer but not statistically significant (12.5 vs. 64.5 days, p=0.09). However, 1-, 3-, 5-year survival were not different (77.3%, 70.2% and 63.2%, each). Causes of death were mainly infection in 9, and postoperative bleeding in 3. Conditional 5 years survival for 26 patients who survived 1 year was 89.5%. During long term follow-ups, 7 cases of bronchial stenosis occurred.

Conclusion : Despite the high percentage of patients receiving preoperative intensive care, transplantation results were not inferior to international results. In this study, the survival rate was not statistically different in preoperative ECMO/ventilator group despite of longer ICU stay.


책임저자: Se Hoon Choi
Department of Thoracic and Cardiovascular Surgery, Asan Medical Center, Ulsan University College of Medicine, Seoul, Republic of Korea
발표자: Se Hoon Choi, E-mail : choishn@gmail.com

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