초록접수 현황
| 17F-017 | 포럼 발표 |
Surgical Outcome of Native Valve Endocarditis
Bong Suk Park, Weon Yong Lee
Department of Thoracic and Cardiovascular Surgery, Sacred Heart Hospital, Hanllym University College of Medicine, Gyeonggi-do, Republic of Korea
Purpose : The aim of this study was to evaluate early and interim results following surgical treatment for native valve endocarditis (NVE) and to investigate risk factors associated with survival.
Methods : Data pertaining to patients characteristics, operative and postoperative variables, and early and interim survival indices for surgical treatment of NVE were retrospectively obtained from our institutional database for the period between March 2003 and February 2017. Data comparisons and survival calculations were performed using the Chi-squared test, logistic regression analysis, and the Kaplan-Meier method with IBM SPSS Statistics.
Results : 29 patients underwent surgery for NVE, and the mean follow-up duration was 61.2 months. The affected valves were mitral in 20 and aortic valve in 9 patients. Causative organisms were Streptococci in 14, Staphylococci in 7, miscellaneous in 2, and unidentified in 6 patients. Preoperatively, 9 patients suffered from cerebral embolism with or without symptoms. Early mortality was noted to be 13.7% (4/29). Major postoperative complications occurred in 6 patients (20.7%). Six-month and three-year survival rates were 82.8% and 76.2%, respectively. Causative organisms, affected valves, and embolic events did not reveal statistically significant differences in the surgical outcomes. End-stage renal disease (ESRD) and insufficient use of antibiotics were found to be independent risk factors affecting early mortality (p = 0.042 and p = 0.01, respectively) and overall survival (p = 0.005 and p = 0.046, respectively).
Conclusion : Surgical treatment for NVE is associated with considerable mortality and morbidity. ESRD and insufficient use of antibiotics show a significant correlation with unfavorable outcomes.
Methods : Data pertaining to patients characteristics, operative and postoperative variables, and early and interim survival indices for surgical treatment of NVE were retrospectively obtained from our institutional database for the period between March 2003 and February 2017. Data comparisons and survival calculations were performed using the Chi-squared test, logistic regression analysis, and the Kaplan-Meier method with IBM SPSS Statistics.
Results : 29 patients underwent surgery for NVE, and the mean follow-up duration was 61.2 months. The affected valves were mitral in 20 and aortic valve in 9 patients. Causative organisms were Streptococci in 14, Staphylococci in 7, miscellaneous in 2, and unidentified in 6 patients. Preoperatively, 9 patients suffered from cerebral embolism with or without symptoms. Early mortality was noted to be 13.7% (4/29). Major postoperative complications occurred in 6 patients (20.7%). Six-month and three-year survival rates were 82.8% and 76.2%, respectively. Causative organisms, affected valves, and embolic events did not reveal statistically significant differences in the surgical outcomes. End-stage renal disease (ESRD) and insufficient use of antibiotics were found to be independent risk factors affecting early mortality (p = 0.042 and p = 0.01, respectively) and overall survival (p = 0.005 and p = 0.046, respectively).
Conclusion : Surgical treatment for NVE is associated with considerable mortality and morbidity. ESRD and insufficient use of antibiotics show a significant correlation with unfavorable outcomes.
책임저자: Weon Yong Lee
Department of Thoracic and Cardiovascular Surgery, Sacred Heart Hospital, Hanllym University College of Medicine, Gyeonggi-do, Republic of Korea
발표자: Bong Suk Park, E-mail : pbsthr@hallym.or.kr