초록접수 현황
| 17F-029 | 포스터 발표 |
Predictive Risk Factors of Acute Kidney Injury after Coronary Artery Bypass Surgery under Cardiopulmonary Bypass
Jin Tae Kwon¹, Tae Eun Jung², Jun Young Do³, Dong Hyup Lee²
¹Department of Chest Surgery, Bundang Jesaeng Hospital, Gyeonggi-do, Republic of Korea., ²Department of Thoracic and Cardiovascular Surgery, Yeungnam University Medical Center, Yeungnam University College of Medicine, Daegu, Republic of Korea., ³Division of Nephrology, Department of Internal Medicine, Yeungnam University Medical Center, Yeungnam University College of Medicine, Daegu, Republic of Korea
Purpose : The aims of our study are to define the incidence of acute kidney injury (AKI) and identify preoperative and operative risk factors for developing AKI after coronary artery bypass grafting (CABG).
Methods : In the retrospective study, 210 consecutive patients who underwent CABG from January 2007 to March 2016 were included. The patients were divided into AKI group (Group 1) and without AKI group (Group 2) after operation. AKI definition used internationally standardized criteria (serum creatinine >1.5 times baseline, elevation in >0.3 mg/dl). Measurements of serum creatinine were collected preoperative and peak level during immediate postoperative and daily for five days.
Results : The postoperative peak serum creatinine level was increased 1.26±0.36 times than preoperative studies. AKI occurred in 40.1% patients (85/210). Age (Group 1; 67.2±8.2, Group 2; 63.7±8.6, p=0.004), body surface area (Group 1; 1.64±0.16, Group 2; 1.71±0.16, p=0.003), body weight (Group 1; 60.7±10.2, Group 2; 64.1±10.0, p=0.017) were statistically significant. Preoperative hemoglobin, BUN, creatinine, eGFR and CRP were not significant. Female gender (OR;1.88, p=0.044), preoperative proteinuria (OR;2.711, p=0.011) and emergent operation (OR; 2.641, p=0.035) were risk factors in univariate analysis. DM, hypertension, medication of ACEI and ARB were not significant. As operative factors, total pump time, aortic cross clamp time and transfusion were not significant. Preoperative proteinuria (Odds Ratio; 2.396, p=0.035) was a risk factors in multivariate analysis.
Conclusion : Preoperative proteinuria was independent predictors of postoperative AKI in patient undergoing CABG. It could be used to identify patients at high risk for AKI.
Methods : In the retrospective study, 210 consecutive patients who underwent CABG from January 2007 to March 2016 were included. The patients were divided into AKI group (Group 1) and without AKI group (Group 2) after operation. AKI definition used internationally standardized criteria (serum creatinine >1.5 times baseline, elevation in >0.3 mg/dl). Measurements of serum creatinine were collected preoperative and peak level during immediate postoperative and daily for five days.
Results : The postoperative peak serum creatinine level was increased 1.26±0.36 times than preoperative studies. AKI occurred in 40.1% patients (85/210). Age (Group 1; 67.2±8.2, Group 2; 63.7±8.6, p=0.004), body surface area (Group 1; 1.64±0.16, Group 2; 1.71±0.16, p=0.003), body weight (Group 1; 60.7±10.2, Group 2; 64.1±10.0, p=0.017) were statistically significant. Preoperative hemoglobin, BUN, creatinine, eGFR and CRP were not significant. Female gender (OR;1.88, p=0.044), preoperative proteinuria (OR;2.711, p=0.011) and emergent operation (OR; 2.641, p=0.035) were risk factors in univariate analysis. DM, hypertension, medication of ACEI and ARB were not significant. As operative factors, total pump time, aortic cross clamp time and transfusion were not significant. Preoperative proteinuria (Odds Ratio; 2.396, p=0.035) was a risk factors in multivariate analysis.
Conclusion : Preoperative proteinuria was independent predictors of postoperative AKI in patient undergoing CABG. It could be used to identify patients at high risk for AKI.
책임저자: Dong Hyup Lee
Department of Thoracic and Cardiovascular Surgery, Yeungnam University Medical Center, Yeungnam University College of Medicine, Daegu, Republic of Korea
발표자: Dong Hyup Lee, E-mail : dhlee@med.yu.ac.kr