Perioperative Risk Factors in Surgical Lung Biopsy for the Diagnosis of Interstitial Lung Disease.
Jun Hee Lee, Eunjue Yi, Jae Ho Chung, Kwang Taik Kim, Sungho Lee
Department of Thoracic and Cardiovascular Surgery, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Republic of Korea
Purpose : The aim of this study is to evaluate mortality and morbidity after surgical lung biopsy in patients with interstitial lung biopsy, and investigate perioperative risk factors for complications.
Methods : Medical records of patients who had undergone surgical lung biopsy for the diagnosis of interstitial lung diseases were reviewed retrospectively between 2005 and 2015 in our institute. Enrolled patients were divided into 3 groups; (1) Group 1; Patient with prepared operation which scheduled before their admission. (2) Group 2; Patient with operation determined after medical therapy. (3) Patients with emergent operation followed by steroid therapy. Mortality and complications rates were evaluated, and perioperative risk factors were investigated.
Results : A total of 132 patients were included in this study. Overall complication rates were 19.7% (26 cases). 30-day in-hospital mortality rates were 1.5% (2 patients) and those of 90-day were 3.0% (4 patients). Complication rates were significantly different between the three groups (p=0.060), but not with readmission rates (p=0.071). Patients in Group 1 revealed only class I or II complications, and no mortalities. In univariate analysis, risk factors for complications were NYHA class at the time of admission, preoperative CRP level, patients in Group 3 and elevated oxygen demands after operations (p=0.018, 0.020, 0.028 and <0.000 respectively). In multivariate analysis, elevated oxygen demands were the only significant risk factor for complications (p<0.000).
Conclusion : Prepared surgical lung biopsy for interstitial lung disease is feasible with reasonable morbidity. Elevated oxygen demand after this surgery could imply postoperative outcomes.
책임저자: Sungho Lee
Department of Thoracic and Cardiovascular Surgery, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Republic of Korea
발표자: Jun Hee Lee, E-mail : viking99@hanmail.net